I am thrilled to announce that I have joined Dr. Anny Xiaobo Zhou's lab at Harvard Medical School's Brigham and Women's Hospital. Dr. Zhou's lab is dedicated to uncovering the molecular mechanisms of pulmonary diseases, such as COPD and asthma, by translating human genetic discoveries into translational research questions. (Learn more about the lab here)

From day one, I was struck by how welcoming and supportive everyone in the lab has been. Their kindness and collaborative spirit have made transitioning into this new environment an absolute pleasure.

In this exciting new role, I look forward to leveraging my expertise in fluorescent biosensors to investigate the role of complex signaling activity and the potential role of spatiotemporal signaling activity in these critical diseases. I’m eager to contribute to the lab’s impactful research and collaborate with such an inspiring group of scientists.

Keep an eye out for future projects to come!!

As a dedicated researcher nearing the completion of my Ph.D. in Biochemistry, Molecular, Cellular, and Developmental Biology at UC Davis (expected August 2024), I am actively seeking postdoctoral opportunities in labs focused on live-cell imaging and microscopy. My expertise lies in lung epithelial inflammatory response, biosensor engineering, cell metabolism, and kinase signaling kinetics. My knowledge set is complemented by robust skills in live cell imaging and data analysis. I'm eager to contribute to innovative research in a dynamic lab environment.

This preprint on bioRxiv investigates the role of ERK signaling in inflammatory responses in human airway epithelial cells. The study characterizes spatiotemporal ERK activity and examines how pro-inflammatory cytokines influence ERK signaling and epithelial barrier function, suggesting potential clinical applications for managing inflammation in conditions like asthma and COPD. Read more.

In this first part of the review series in the Biochemical Journal, the focus is on the mechanisms and models that describe the dynamic behavior of the ERK pathway. The paper delves into optogenetic and live-cell imaging technologies, and the challenges in modeling ERK dynamics, offering insights into the temporal and spatial regulation of this critical signaling pathway. Read more.

This part of a two-part review published in the Biochemical Journal discusses how ERK pathway dynamics influence gene expression programs to control various cellular processes. It highlights the implications of ERK signaling in tissue regulation and disease, providing a comprehensive overview of how ERK activity can be targeted therapeutically. Read more.

Published in eLife, this study explores how the mTORC1-TFEB axis senses nutrients and growth factors to maintain cellular homeostasis. The research used live imaging and multiplexed immunofluorescence to show how mTORC1 signaling continuously adjusts to nutrient availability, offering insights into its role as a metabolic controller at the single-cell level. Read more.